Primary Faculty


	Anna A. DePaoli-Roach, Ph.D. Professor Structure, function, and regulation of protein phosphatases; study of role in diabetes and obesity through knockout and transgenic overexpressing mice.

	X. Charlie Dong, Ph.D. Assistant Professor Gene regulation by hormones and nutrients in metabolic and energy homeostasis; transcriptomic and proteomic dissection of metabolic syndrome including diabetes and obesity.

	A. Keith Dunker, Ph.D. T. K. Li Professor Understanding intrinsically disordered proteins using bioinformatics approaches and laboratory experiments.

	Howard J. Edenberg, Ph.D. Distinguished Professor, Chancellor's Professor, Director of Center for Medical Genomics Regulation of gene expression; genetics of complex diseases; molecular biology of alcohol metabolism and alcoholism.

	Millie M. Georgiadis, Ph.D. Professor, Graduate Admissions Chairman X-ray crystallographic, biochemical, and thermodynamic studies of protein-nucleic acid interactions involved in replication, nuclear export, and temporal gene expression.

	Mark G. Goebl, Ph.D. Professor, Graduate Advisor Molecular biology and genetics of cell division cycle regulatory mechanisms in yeast.

	Maureen A. Harrington, Ph.D. Professor, Associate Director, M.D./Ph.D. Program Regulation and development of innate immune response; TNF signaling; blood cell development.

	Quyen Hoang, Ph.D. Assistant Professor Structural biology of neurodegenerative disease and structure-based drug design.

	Andy Hudmon, Ph.D. Assistant Professor Molecular mechanisms underlying normal and aberrant Ca²⁺ signaling in neurons: kinases, molecular machines, and signaling modules.

	Thomas D. Hurley, Ph.D. Chancellor's Professor, Associate Chairman, Director of Center for Structural Biology X-ray crystallography of enzymes; probing enzyme function through mutagenesis and small molecule discovery; kinetic analysis of enzyme - ligand interactions.

	Suk-Hee Lee, Ph.D. Professor Molecular mechanism of non-homologous end joining repair in humans; Recognition of cisplatin-induced DNA damage in the early stage of nucleotide excision repair.

	Hyun-Suk Lim, Ph.D. Assistant Professor Chemical biology and drug discovery: identification of small molecules that modulate cellular signaling pathways with an emphasis on protein-protein interactions for use as biological probes and therapeutic agents.

	Samy Meroueh, Ph.D. Associate Professor Molecular Design and Characterization of Small Molecules that Target Protein Interactions and Enzymes in Cancer and Neurological Disorders.

	Amber Mosley, Ph.D. Assistant Professor Analysis of protein-protein interaction networks and post-translational modifications that regulate RNA Polymerase II transcription using protein mass spectrometry and genomics

	Lawrence Quilliam, Ph.D. Professor Regulation of cell signaling and cancer by Ras family GTPases.

	Peter J. Roach, Ph.D. Distinguished Professor , Chancellor's Professor, Director of Center for Diabetes Research Glycogen metabolism and its regulation. Covalent phosphorylation of glycogen, its metabolism and Lafora disease. Vesicular trafficking of glycogen to the lysosome and autophagy. Mouse models with genetically modified glycogen stores and blood glucose homeostasis.

	Yuichiro Takagi, Ph.D. Associate Professor Mechanism of eukaryotic gene regulation by RNA polymerase II.

	Mu Wang, Ph.D. Associate Professor, Director of Proteomics Core The use of proteomic technologies such as label-free mass spectrometry-based shotgun protein quantification and multiple-reaction-monitoring (MRM) for biomarker development.

	Ronald C. Wek, Ph.D. Showalter Professor Mechanisms for coping with cellular stress. Regulation of gene expression by eIF2 kinases.

	Clark D. Wells, Ph.D. Associate Professor Causal relationships between differentiation and growth control in Breast Cancer Development; Cross-talk between Cell polarity, HIPPO/YAP dependent transcription and ErbB/MAPK signaling.

	Qi-Zhuang Ye, Ph.D. Associate Professor Proteases and Protein Phosphatases: Enzyme Catalysis and Inhibition, Protein Structure and Function, and Drug Discovery.

	Zhong-Yin Zhang, Ph.D. Robert A. Harris Professor and Chairman Chemical biology, signaling mediated by tyrosine dephosphorylation, targeting protein tyrosine phosphatases for the treatment of cancer, diabetes/obesity, autoimmune disorders, and infectious diseases.